Pathological polyploidy in liver disease
نویسندگان
چکیده
منابع مشابه
Pathological aspects of fatty liver disease
......................................... Received: 11-02-14 Accepted: 21-02-14 Abstract In a normal human liver 5% of its mass consists of lipids. When deposition of fat increases, the terms most often used are fatty liver or steatosis. This includes non-alcoholic fatty liver disease whose acronym is NAFLD and alcoholic liver disease (ALD). A liver biopsy is still considered to be the gold sta...
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Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder of our times. The spectrum of this disease goes from steatosis to non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma. NAFLD can appear in the context of many condi‐ tions. Probably, NAFLD could be a component of metabolic syndrome, with its complete phenotypic expression: insulin resistance, obe...
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Polyploidization is a state in which cells possess more than two sets of homologous chromosomes, which occurs frequently in nature [1]. In Mammals, whole organism polyploidy is usually lethal; however, some tissues develop a certain degree of polyploidy during their normal lifecycle. Polyploid cells are generated because of cell fusion or abnormal cell division (e.g. endoreplication, mitotic sl...
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Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation be...
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results inter-observer agreement of the pathology scores based on nas scoring system was acceptable for steatosis, lobular inflammation, and fibrosis, but not for hepatocyte ballooning. the intra-observer agreement was acceptable in all scales, with lowest intra-class correlation observed for lobular inflammation. materials and methods the anonymous liver biopsy samples of 100 consecutive nafld...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2015
ISSN: 0270-9139
DOI: 10.1002/hep.27908